The area of pain neuroscience has made great strides in the last 10 years in identifying underlying mechanisms, that when targeted with the correct treatment, can make a significant impact on a patient’s life. Science tells us that exercise is the best treatment for a chronic pain patient. As allied healthcare professionals, we improve physical functioning and since the world is experiencing a chronic pain epidemic, we need to play our part in educating and empowering our patients to effectively manage their own pain. As the last link in the chain of healthcare professionals, we often come face to face with chronic pain patients that have been unable to find any relief of their pain. We also spend more time with the patient and can therefore make a significant positive impact on someone’s wellbeing. This overview, will change your mindset and awaken a need for further knowledge into this often poorly understood population. Lets go and be the change!