The term “Difficult Patient” refers to a group of patients with whom a Health Care Provider (HCP) may have trouble forming a normal therapeutic relationship. The care of these patients can present many ethical dilemmas, ranging from issues of patient autonomy to questions of appropriate use of resources, which the HCP must be prepared to handle. Encounters with these patients also challenge HCP to explore and cultivate many of the character traits and virtues necessary to being humane, caring and an ethical Practitioner.